Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and m
Human,Mouse(predicted: Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
IHC-P,IHC-F,IF,Flow-Cyt
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.